What is PSA Test? What Does Elevated PSA Mean?
May 23, 2026 Prof. Dr. Orçun Çelik Prostate Diseases

What is PSA Test? What Does Elevated PSA Mean?

AI Summary

PSA (Prostate Specific Antigen) is a protein produced by the prostate gland. Elevated PSA doesn't always mean cancer; BPH and infection can also raise levels.

What is the PSA Test?

PSA (Prostate Specific Antigen) is a protein produced by the prostate gland that can be measured in blood. The PSA test is the most important screening tool for early detection of prostate cancer.

Normal PSA Values by Age

  • 40-49 years: 0-2.5 ng/mL
  • 50-59 years: 0-3.5 ng/mL
  • 60-69 years: 0-4.5 ng/mL
  • 70+ years: 0-6.5 ng/mL

Causes of Elevated PSA (Non-Cancer)

  • Benign prostatic hyperplasia (BPH)
  • Prostatitis (infection/inflammation)
  • Urinary tract infection
  • Recent ejaculation
  • Cycling
  • Urinary catheter

When to Get PSA Testing

  • Age 50+: All men should discuss annual screening
  • Age 45+: Family history of prostate cancer
  • Age 40+: First-degree relative with early prostate cancer

What Happens with High PSA?

  1. Treat infection if present, repeat in 4-6 weeks
  2. Free/total PSA ratio and PSA density calculation
  3. Multiparametric prostate MRI (PI-RADS scoring)
  4. MR-Fusion biopsy if suspicious (PI-RADS 3-5)

PSA Evaluation in Izmir

Prof. Dr. Orçun Çelik provides comprehensive PSA evaluation, multiparametric MRI interpretation, and MR-fusion biopsy at Izmir Bazekol Hospital.

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